Case studies

Leak-free, low-noise circulation pump for cooling and temperature control circuits in bioreactors and fermenters in OEM medical technology

MARCH M1 – compact, magnetic-drive 24V centrifugal pump for reliable temperature control in biotechnology and medical technology systems

Magnetic-drive centrifugal pump of the M series made of plastic
Magnetic-drive centrifugal pump of the M series

In modern fermentation and bioreactor systems, precise temperature control is an essential factor for process stability, reproducibility and product quality. Cooling and temperature control circuits must reliably remove process heat or supply it in a targeted way, without fluctuations affecting the biological processes.

The magnetic-drive MARCH M1 is suited to these requirements as a compact, leak-free and low-noise circulation pump with a 24V BLDC/EC drive. It was designed for applications in which a stable flow rate, high operational reliability, simple OEM integration and low-maintenance continuous operation are decisive.

Enquiry data / process requirements

ApplicationCooling and temperature control circuits in bioreactors, fermenters and medical technology peripherals
Typical mediaWater/glycol and comparable temperature control media
Requirementstable, continuous flow rate for high control quality of the temperature control
Operating modesuitable for continuous operation in typical 24/7 applications
Key criterialow noise, minimised leakage risk, high operational reliability
Integrationcompact design, common connections, reliable start-up behaviour

Pump type used / key technical data

M1 series, magnetic-drive centrifugal pump with 24V BLDC/EC drive

Drive24V EC/BLDC drive, brushless, typ. 7 W, electronically commutated with integrated control
Electrical connectionsimple connection via two leads (+/-)
Designspace-saving thanks to external rotor
Noise levelwhisper operation at ≤ 40 dB(A)
Max. flow rateup to 8.4 l/min
Max. headup to 4 mWC
Wetted materialsPP, POM (Delrin), PSU
Temperature ranges (depending on material)PP up to 70 °C, POM up to 90 °C, PSU up to 121 °C
Connections (depending on model)3/8″ female thread, 1/4″ NPT, hose connections 3/8″ and 1/2″

The application

Fermentation and bioreactor systems are used in highly critical biotechnological processes, from early research and process development to industrial production of active ingredients and vaccines. In these applications, parameters such as temperature, pH value, oxygen supply and feed regime directly influence cell growth, yield and product quality.

A particularly safety-relevant part of the plant periphery is temperature control. Cooling and temperature control circuits ensure that heat is reliably removed or supplied as needed. Even small temperature deviations can impair process stability and have a negative effect on sensitive biotechnological processes.

In vaccine production, active ingredients are often processed and diluted after cultivation, transferred to sterile single-use containers and then transferred to downstream production and filling plants. This process chain places particularly high demands on the operational reliability and dependability of the peripheral components used.

Why a magnetic-drive 24V centrifugal pump?

In sensitive medical technology and biotechnology applications, leak-free, low-maintenance and low-noise pump solutions are particularly in demand. The magnetic-drive design of the MARCH M1 avoids dynamic seals in the classic sense and thereby significantly reduces the risk of leaks and the maintenance effort.

The compact 24V BLDC/EC drive makes the pump ideal for OEM integration into devices, skids and modular process systems. At the same time, its quiet running supports use in laboratory environments, diagnostic systems, clinical areas and other noise-sensitive applications.

With a flow rate of up to 8.4 l/min and a head of up to 4 mWC, the M1 offers a suitable performance profile for many cooling and temperature control tasks in biotech, MedTech and equipment peripherals.

Further medical technology applications of the M1

  • Patient thermoregulation: blood and infusion warmers
  • Blood bank and cell/gene: plasma/FFP thawing, cell material thawing, therapy manufacturing peripherals
  • Bioprocess peripherals: bioreactor/fermenter temperature control, single-use skids, modular process modules
  • Minimally invasive surgery: irrigation/fluid management and fluid warming
  • Urology / laser MedTech: water cooling circuits in laser systems

Why the MARCH M1 is the right choice

  • Leak-free thanks to magnetic coupling: reduces the risk of leaks and minimises maintenance effort in sensitive environments.
  • 24V BLDC/EC drive: ideal for OEM integration into medical devices and skids.
  • Very quiet operation: suitable for noise-sensitive laboratory and clinical areas.
  • Suitable performance profile: up to 8.4 l/min and up to 4 mWC for cooling and temperature control circuits.
  • Flexible material options: PP, POM and PSU for different temperature and media requirements.
  • Quick integration: compact design and common connection options simplify design and service.

Further information

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